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Usually just a small amount of food is enough, but your pharmacist should talk to you the first time you fill the prescription and tell you if more is necessary
I'm not a doctor, so don't take my word for it, but I've heard the same as robolemmy. To be a bit less abstract, my understanding is you eat enough so that your stomach will digest normally instead of just handling the medicine as a tiny bit of something caustic. A granola bar should be fine, but you might do better with a slice of bread or something a tad easier to digest. Then again, I don't think it matters all that much.
So you trick your stomach like you'd trick a dog by hiding medicine in their food?
Nah, that's all about getting the dog to actually swallow the pill.
For us, it is about buffering the concentration. Even aspirin can upset your stomach (well, SOME people's stomachs) such that making "Bufferin" was once a big deal. It was just aspirin with a buffering agent, but having a buffer really mattered for some people.