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As many as 1 in 5 people won't lose weight with GLP-1 drugs, experts say (apnews.com)

submitted 1 day ago by MicroWave@lemmy.world to c/health@lemmy.world

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Summary

As many as 1 in 5 patients may not lose significant weight with GLP-1 drugs like Wegovy and Ozempic, despite their popularity and effectiveness in clinical trials.

Experts attribute this variability to genetic, hormonal, and brain-based differences in regulating energy, as well as factors like sleep apnea or medications that hinder weight loss.

Non-responders often face frustration, but doctors stress alternative options, including different medications, lifestyle adjustments, or older treatments.

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[–] marine_mustang@sh.itjust.works 17 points 1 day ago (2 children)

“As many as” 20% so, less than 20%? So it’s more than 80% effective?

[–] reallykindasorta@slrpnk.net 14 points 1 day ago

The article is about that 20% and how they’re feeling pretty shitty after taking a drug that works for 80% and not seeing weightloss despite the significant hype. It’s basically obesity experts trying to calm expectations slightly—the drug works for a lot of people but you can’t count on it being a magic bullet for everyone.

[–] originalucifer@moist.catsweat.com 6 points 1 day ago

hahah yeah what an ass-backwards way of attempting shit on efficacy