Bebo

From forming bound states to normal scattering, many possibilities abound for matter-antimatter interactions. So why do they annihilate? There’s a quantum reason we simply can’t avoid.

Clinical relevance of miRNAs as biomarkers is growing due to their stability and detection in biofluids. This study has identified miR-519a-3p as a potential early biomarker for Alzheimer’s, linked to prion protein expression. This molecule is directly associated with the expression of the cellular prion protein located on the surface of nerve cells. miR-519a-3p may potentially be used as a biomarker of preclinical stages of the disease.

https://www.sciencedirect.com/science/article/pii/S0925443924001765?via%3Dihub (open access)

The perception of taste is remarkably complex, not only on the tongue but in organs throughout the body.

The idea that specific tastes are confined to certain areas of the tongue is a myth that “persists in the collective consciousness despite decades of research debunking it.” Also wrong: the notion that taste is limited to the mouth.

https://www.nejm.org/doi/pdf/10.1056/NEJMra2304578

This study focuses on the manipulation of the plexin-B1 protein to enhance the brain’s ability to clear amyloid plaques in Alzheimer’s disease, opening avenues for future therapeutic strategies to potentially halt the progression of the disease

https://www.nature.com/articles/s41593-024-01664-w

This study has identified the anterior cingulate cortex (ACC) as a key area in the brain responsible for sensory hypersensitivity in autism spectrum disorders. Utilizing a mouse model with a Grin2b gene mutation, heightened neural activity and connectivity in the ACC was observed. Suppressing this hyperactivity normalized the sensory hypersensitivity, offering new insights into treatment options

https://www.nature.com/articles/s41380-024-02572-y (open access)

Really enjoyed this one.

Brain-machine interfaces implanted in the participants of this study in the supramarginal gyrus (SMG) and primary somatosensory cortex (S1) were successfully able to decode both internally spoken and vocalized words.

https://www.nature.com/articles/s41562-024-01867-y?utm_source=Live+Audience&utm_campaign=1586f44658-nature-briefing-daily-20240514&utm_medium=email&utm_term=0_b27a691814-1586f44658-52006460 (open access)

The engineering of artificial cells requires a reconfigurable cytoskeleton that can organize at distinct locations and dynamically modulate its structural and mechanical properties. This study combines peptide self-assembly with DNA programmability to realize a synthetic cytoskeleton in droplets showing that programmable peptide–DNA nanotechnology approach is a powerful platform towards the construction of functional, fully artificial cells.

https://www.nature.com/articles/s41557-024-01509-w (open access)

Internet Watch Foundation has found a manual on dark web encouraging criminals to use software tools that remove clothing. The manipulated image could then be used against the child to blackmail them into sending more graphic content, the IWF said.

Breast cancer diagnoses in women under 50 have increased significantly in the past two decades, primarily driven by estrogen-receptor positive tumors. This research highlights the importance of early detection and the need for prevention strategies. Prevention efforts in young women need to adopt a targeted approach to address racial disparities in incidence rates observed at different age phases.

https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2814306 (open access)

This study has established specific ultrasound parameters in the use of low-intensity, low-frequency ultrasound stimulation (LILFUS), designed to mimic the brainwave patterns of theta and gamma oscillations observed during learning and memory processes to induce predictable and long-lasting changes in brain function.

https://www.science.org/doi/10.1126/sciadv.adk3198 (Open access)