Statistics generally show that people with guns in their house are much more likely to be fatally shot. Suicide is a big factor, as are domestic disputes. It seems that generally, there are points in many people's lives of extreme emotional anguish or rage, and if they have access to a firearm at that point they will use it, with deadly consequences. On the other side of the equation, successfully preventing harm with a firearm is comparatively more rare. In other words, owning guns causes more harm than it prevents.
At a societal level the same picture more or less bears out: the more guns available in a community, the higher the incidence rates of gun violence. This is true independent of crime levels, income, or demographics.
It therefore seems desirable to attempt to reduce the number of guns in private ownership. For the United States, that's quite a complicated task, and I don't see any realistic path to a gun-free society. Especially not with ~50% of the country opposed to such a goal. Probably the first step would have to be to increase public support for gun control, otherwise all efforts are futile.