seven year itch
Wow - I had never put those two together before.
Anyway, Memory Alpja states that intensive meditation is also used to alleviate the problems associated with pon farr.
What doesn’t make in-universe sense to me is that the condition comes from a neurochemical cascade. Even in our time, we recognize many of these conditions and have targeted drugs and therapies for them. Surely a society that is medically and technologically more advanced than ours by orders of magnitude would be able to simply treat the condition.
As a plot point it makes sense, and Roddenberry both personally and as a person of his time saw things like brain processes as strange and mysterious. It allowed them to play with the still evolving character of Spock and with Vulcans in general. It allowed them to do that “put a human condition into an alien and turn it up to 11” kind of thing they loved so much. The same would go for Lon Suder, of course.
They just get really hand-wavey around medical questions.