this post was submitted on 23 Nov 2024
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Summary

As many as 1 in 5 patients may not lose significant weight with GLP-1 drugs like Wegovy and Ozempic, despite their popularity and effectiveness in clinical trials.

Experts attribute this variability to genetic, hormonal, and brain-based differences in regulating energy, as well as factors like sleep apnea or medications that hinder weight loss.

Non-responders often face frustration, but doctors stress alternative options, including different medications, lifestyle adjustments, or older treatments.

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[–] paraphrand@lemmy.world 5 points 1 day ago

What, you’re saying weight is complicated and not just down to one factor for everyone?!

It’s cool we have proof of this via the magic drugs.