Yes, absolutely. I can enjoy second reads, but discovery can be an important part of the journey. Will I get as invested in character A if I know in advance they're going to get killed off? If I don't get as invested, doesn't that lessen the emotional impact and thereby diminish the story?

Someone mentioned that we all know how The Titanic ends. But the fate of the Titanic was never more than a plot device, and the ship wasn't the focus of the story.

I was lucky to have been utterly ignorant about Sixth Sense - I hadn't even heard there was a twist ending, so I wasn't looking for one, and the ending was consequently both a surprise and so much more impactful than if I'd known how it ended.