For me it's Corner Gas. I still think it's pretty funny and there's a decent amount of references to Canadian stuff but not enough to be off-putting. I feel like an American wouldn't be confused watching it even if some of the references get a bit dated overtime.
I have only seen a bit of the animated version in waiting rooms.
SCTV, specifically Bob & Doug. SCTV was asked to add two minutes of explicitly Canadian content to an already very Canadian show and the result was the Great White North and the Mackenzie brothers.
Along with SCTV, Bizarre and Kid in the Hall were god damned hilarious! They were like a maple flavoured Monty Python.
I forgot about Bizarre. God I miss Super Dave.